Risk of progression from undifferentiated arthritis to rheumatoid arthritis: the effect of the PTPN22 1858T-allele in anti-citrullinated peptide antibody positive patients
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منابع مشابه
The influence of anti-cyclic citrullinated peptide on anticentromere antibody-positive rheumatoid arthritis patients: authors' response
regarding the infl uence of anti-cyclic citrullinated peptide (CCP) on anticentromere antibody (ACA)-positive patients suff er ing from rheumatoid arthritis (RA) [1]. Th eir fi ndings explore the eff ect of ACA positivity in a patient group diff erent from the cohort of primary Sjögren syndrome (SS) patients we chose to study [2]. Due to the diff erent study population and the retrospective nat...
متن کاملThe influence of anti-cyclic citrullinated peptide on anticentromere antibody-positive rheumatoid arthritis patients
that anticentromere antibody (ACA)-positive primary Sjögren’s syndrome (SS) shows a clinical phenotype intermediate between ACA-negative SS and systemic sclerosis (SSc) [1]. In our past study investigating the clinical features of 62 patients with positive ACA, only one patient had typical CREST syndrome, 9 patients had Raynaud’s phenomenon (8 with sclerodactyly, telangiectasia or calcinosis), ...
متن کاملThe PTPN22 1858C/T polymorphism is associated with anti-cyclic citrullinated peptide antibody-positive early rheumatoid arthritis in northern Sweden
The PTPN22 1858C/T polymorphism has been associated with several autoimmune diseases including rheumatoid arthritis (RA). We have shown that carriage of the T variant (CT or TT) of PTPN22 in combination with anti-cyclic citrullinated peptide (anti-CCP) antibodies highly increases the odds ratio for developing RA. In the present study we analysed the association between the PTPN22 1858C/T polymo...
متن کاملAnti-Cyclic Citrullinated Peptide Antibody-Positive Meningoencephalitis in the Preclinical Period of Rheumatoid Arthritis
Rheumatoid meningoencephalitis (RM) is a rare complication of rheumatoid arthritis (RA). This report describes a 63-year-old man with complaints of high-grade fever, headache, and vomiting for several days before admission. Both his serum and cerebrospinal fluid were positive for anti-cyclic citrullinated peptide (CCP) antibody and rheumatoid factor, and contrast-enhanced fluid-attenuated inver...
متن کاملThe role of Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Antibody in Diagnosis of Rheumatoid Arthritis
Background: Rheumatoid Factor (RF) occurs in 7090% of patients with established rheumatoid arthritis (RA). Anti-cyclic citrullinated peptide antibody (Anti-CCP) detection may be used to confirm the diagnosis of RA in patients with uncharacterized chronic inflammatory arthritis. This study is an attempt to evaluate the role of RF and anti-CCP in the diagnosis and prognosis of rheumatoid arthriti...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2007
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/kem006